DATASHEET
Formulation
Yellow lyophilized solid
Storage:
-20°C
Product Information:
Ansamycin antibiotic. Inhibits HSP90 and associated client proteins including v-Src, Bcr-Abl, Raf-1 and ErbB21,2. Reverts tyrosine kinase-induced oncogenic transformation without direct inhibition of phosphorylation activity1. Inhibits angiogenesis in a rat retinopathy model3.
Description:
CAS Number: 70563-58-5<br></br>Chemical Name: (15R)-17-Demethoxy-15 methoxy-11-O-methyl-geldanamycin<br></br>Molecular Weight: 574.68<br></br>Formula: C30H42N2O9<br></br>Solubility: DMSO (6 mg/ml)<br></br>Physical Properties: Yellow lyophilized solid<br></br>Purity: 98% by HPLC NMR (Conforms)