bs-83713C [Life Science]
GW3965 HCl
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Formulation White solid

Storage: -20°C

Product Information:

GW3965 is a potent and selective LXR agonist, activating human LXRα and β in cell-based reporter gene assays (EC50=190 and 30 nM respectively).1 Since LXR is a master regulator of cholesterol and fatty acid metabolism, GW3965 exerts a variety of effects including antiatherosclerotic2, antiinflammatory3 as well as antinociceptive4 and alteration of fat tissue distribution5. Orally active.

Description:

CAS Number: 405911-17-3<br></br>Chemical Name: 3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-benzeneacetic acid, hydrochloride<br></br>Molecular Weight: 618.52<br></br>Formula: C33H31ClF3NO3 • HCl <br></br>Solubility: DMSO (48 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC (NMR Conforms)

Size: 5mg, 25mg

Applications: Life Science

For research use only. Not intended for diagnostic or therapeutic use.