bs-83731C
[Life Science]
SCR7 pyrazine
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
SCR7 pyrazine enhances the efficiency of precise genome editing with CRISPR/Cas9 up to 19-fold via inhibition of nonhomologous end joining (NHEJ).1,2 May be employed in an optimized CRISPR/Cas9 method to target methylation in a site-specific manner enabling maintenance of gene silencing in vitro and in vivo.3 SCR7 pyrazine exhibits greater activity against DNA ligases I and III than DNA ligase IV.4 Induces cancer cell death via inhibition of NHEJ and potentiates the effect of double strand break-inducing therapeutic modalities.4,5
Description:
CAS Number: 14892-97-8<br></br>Chemical Name: 2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone<br></br>Molecular Weight: 332.38<br></br>Formula: C18H12N4OS<br></br>Solubility: DMSO (35 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: >98% by TLC NMR (Conforms)
Size: 5mg,25mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.