bs-83745C
[Life Science]
Thiothixene
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Thiothixene is a clinically useful typical antipsychotic.1 It acts as an antagonist at multiple receptors including dopamine D2 and D3 (sub-nanomolar), histamine H1, serotonin 5-HT7, and α1/2-adrenergic. Thiothixene stimulates efferocytosis, the phagocytic removal of apoptotic cells by macrophages, via increased expression of the retinol-binding protein receptor Stra6L leading to arginase 1 production.2 A potential new use for an old drug to facilitate the removal of diseased tissue.
Description:
CAS Number: 3313-26-6<br></br>Chemical Name: ((Z)-N,N-Dimethyl-9-[3-(4-methyl-1-iperazinyl)propylidene]thioxanthene-2-sulfonamide<br></br>Molecular Weight: 443.62<br></br>Formula: C23H29N3O2S2<br></br>Solubility: DMSO (20 mg/ml) with warming<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC, NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.