bs-83760C
[Life Science]
XI-011
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
XI-011 activates p53 by inhibiting expression of one of its negative regulators, MDM4 (MDMX).1 It was able to induce apoptosis in MCF-7 breast cancer cells. XI-011 acted synergistically with cisplatin in inducing apoptosis in head and neck cancer cells.2 It also induced apoptosis in several cervical cancer in vitro and in vivo.3 XI-011 displayed efficacy in treating lung fibrosis in an MDM4-dependent manner.4
Description:
CAS Number: 59474-01-0<br></br>Chemical Name: (10-Methylanthracen-9-yl)methyl carbimidothioate hydrochloride<br></br>Molecular Weight: 316.85<br></br>Formula: C17H16N2S·HCl<br></br>Solubility: DMSO (25 mg/ml) <br></br>Physical Properties: Yellow solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.