bs-83765C
[Life Science]
Sotrastaurin
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Orange solid
Storage: -20°C
Product Information:
Sotrastaurin is a highly selective and potent (IC50’s for PKC isotypes: α = 2.1 nM, ß1 = 2.0 nM, δ = 1.3 nM, ε = 6.2 nM, η = 6.1 nM, Θ = 1.0 nM) pan-PKC inhibitor.1 Potent immunomodulatory agent that inhibits early T-cell activation and displays potential for the prevention of transplant rejection and the treatment of inflammatory diseases.2,3 Sotrastaurin has anticancer activity in various cancer models including breast4, CLL5, ocular melanoma6, and B-cell lymphoma7.
Description:
CAS Number: 425637-18-9<br></br>Chemical Name: 3-(1H-Indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione<br></br>Molecular Weight: 438.49<br></br>Formula: C25H22N6O2<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Orange solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.