bs-83767C
[Life Science]
Indacaterol maleate
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White to off-white solid
Storage: -20°C
Product Information:
Indacaterol maleate is a full agonist (pEC50 = 8.06) of the human ß2 adrenoceptor.1,2 Clinically important drug for the treatment of chronic obstructive pulmonary disease. Indacaterol blocked colorectal cancer progression in vitro (IC50 = 19.01 µM) and in vivo via inhibition of the splicing factor SRSF6 by binding to its RRM2 domain.3 It also blocked cell migration in metastatic breast cancer MDA-MB-231 cells by a similar mechanism.4
Description:
CAS Number: 753498-25-8<br></br>Chemical Name: 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one maleate salt<br></br>Molecular Weight: 508.57<br></br>Formula: C24H28N2O3·C4H4O4<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: White to off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 10mg, 50mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.