bs-83809C
[Life Science]
FB23-2
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
FB23-2 is an inhibitor (IC50 = 2.6 µM) of the mRNA m6A demethylase fat-mass- and obesity-associated protein (FTO).1 Displays significant anti-proliferative activity in NB4 (IC50 = 0.8 µM) and MONOMAC6 (IC50 = 1.5 µM) cells. Selective against the RNA demethylase ALKB5. FB23-2 induced myeloid differentiation and apoptosis in acute myeloid leukemia cells. FB23-2 suppressed the proliferation and migration of hepatocellular carcinoma cells via suppressing the expression of the kinase ERBB3 and human tubulin beta class Iva (TUBB4A).2
Description:
CAS Number: 2243736-45-8<br></br>Chemical Name: 2-[2,6-Dichloro-4-(3,5-dimethyl-1,2-oxazol-4-yl)anilino]-N-hydroxybenzamide<br></br>Molecular Weight: 392.24<br></br>Formula: C18H15Cl2N3O3<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.