DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
TJ-M2010-5 is an inhibitor of the toll-like receptor(TLR)/adaptor molecule myeloid differentiation factor 88 (MyD88) signaling pathway, crucial for inflammation and associated with the development of many inflammation-related cancers.1 It ameliorates ischemia-reperfusion injury in various organ models including brain2, liver3, and heart4. TJ-M2010-5 also suppressed proliferation, migration, and invasion in MCF-7 and MDA-MB-231 breast cancer cells.5 It prevented colitis-associated colorectal cancer by impairing myeloid-derived suppressor cells.6
Description:
CAS Number: 1357471-57-8<br></br>Chemical Name: 3-(4-Benzylpiperazin-1-yl)-N-(4-phenyl-1,3-thiazol-2-yl)propanamide<br></br>Molecular Weight: 406.55<br></br>Formula: C23H26N4OS<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC NMR (Conforms)