bs-83822C
[Life Science]
PAT-1251
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
PAT-1251 is a potent (IC50 = 710 nM) inhibitor of LOXL2, a copper-dependent amine oxidase that deaminates lysine and hydroxylysine residues in collagen and elastin. It displayed >400-fold selectivity over LOX as well as high selectivity against the related amine oxidases SSAO, DAO, and MAO-A/B. A potential new therapeutic for the treatment of fibrotic diseases.
Description:
CAS Number: 2098884-53-6<br></br>Chemical Name: (R,R)-trans-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridine-2-yl)oxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride<br></br>Molecular Weight: 435.8<br></br>Formula: C18H17F3N3O3·HCl<br></br>Solubility: DMSO (>50 mg/ml); water (>80 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC (NMR Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.