bs-83836C
[Life Science]
MreB Inhibitor A22
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
A22 disrupts the actin cytoskeleton of bacteria causing defects in morphology and chromosome segregation.1 It is a competitive inhibitor of ATP binding to MreB and has the ability to disassemble the actin cytoskeleton in bacterial cells.1 It displays antibacterial activity against P. aeruginosa (among many others) including multidrug-resistant clinical isolates and points to MreB as a new target for antibacterial development.2 A22 significantly disrupts biofilm formation by interfering with the ability of bacterial cells to maintain shape and adherence to surfaces.3
Description:
CAS Number: 22816-60-0<br></br>Chemical Name: 2-(3,4-Dichloro-benzyl)-isothiourea, hydrochloride<br></br>Molecular Weight: 271.58<br></br>Formula: C8H8Cl2N2S • HCl<br></br>Solubility: Water (6 mg/ml); DMSO (30 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 10mg, 50mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.