bs-83841C
[Life Science]
CID16020046
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800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White to off-white solid
Storage: -20°C
Product Information:
CID16020046 is a selective GPR55 antagonist.1 In HEK293 cells expressing GPR55, the compound behaves as an antagonist on lysophosphatidylinositol (LPI)-mediated Ca2+ release but was inactive on cells expressing CB1 and CB2. It blocks LPI-induced migration of colon cancer cells.2 It displays protective effects against oxidized LDL-induced inflammation3, mitigates advanced glycation end products-induced chondrocyte activation4, and displays anti-inflammatory effects in various cells5,6. A useful tool for studying the role of GPR55 in cellular physiology.
Description:
CAS Number: 834903-43-4<br></br>Chemical Name: 4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid<br></br>Molecular Weight: 425.44<br></br>Formula: C25H19N3O4<br></br>Solubility: DMSO (45 mg/ml)<br></br>Physical Properties: White to off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 5mg,25mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.