bs-8524R-A488 [Conjugated Primary Antibody]
Calcium Sensing Receptor Antibody, ALEXA FLUOR® 488 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Calcium Sensing Receptor

Immunogen Range: 121-220/1078


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 846

Swiss Prot: P41180

Source: KLH conjugated synthetic peptide derived from human Calcium Sensing Receptor/CaSR

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.

Conjugation: ALEXA FLUOR® 488

Excitation/ Emission: 490nm/525nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 118


Cross Reactive Species: Pig

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Huang, Bo, et al. "Chitosan oligosaccharide reduces intestinal inflammation that involves CaSR activation in LPS challenged-piglets." Journal of Agricultural and Food Chemistry (2016).Read more>>
  • Liu H et al. Involvement of calcium-sensing receptor activation in the alleviation of intestinal inflammation in a piglet model by dietary aromatic amino acid supplementation. (2018) Br J Nutr.;120(12):1321-1331.Read more>>
  • Zhang P et al. Differentiation of Rat Adipose-Derived Stem Cells into Parathyroid-Like Cells. Int J Endocrinol. 2020 Jun 12;2020:1860842.Read more>>
  • Nan Gao. et al. Tryptophan Promotes Intestinal Immune Defense through Calcium-Sensing Receptor (CaSR)-Dependent Metabolic Pathways. J Agr Food Chem. 2021;XXXX(XXX):XXX-XXXRead more>>
  • Shasha Chen. et al. Quercetin alleviates zearalenone-induced apoptosis and necroptosis of porcine renal epithelial cells by inhibiting CaSR/CaMKII signaling pathway. FOOD CHEM TOXICOL. 2023 Nov;:114184Read more>>