DATASHEET
Host:
Rabbit
Target Protein:
BASP1
Immunogen Range:
3-100/227
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
10409
Swiss Prot:
P80723
Source:
KLH conjugated synthetic peptide derived from human BASP1/Nap22
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Neuronal axonal membrane protein Nap-22, also designated neuronal tissue-enriched acidic protein or brain acid soluble protein (BASP1), is a Ca2+-dependent calmodulin-binding protein that is important for neuronal sprouting and plasticity. Nap-22 is abundant in brain nerve terminals and is also present in significant amounts in kidney, testis and lymphoid tissue. Nap-22 undergoes N-terminal myristoylation for membrane localization. It has been characterized as a major protein of neuronal rafts, which are known to preferentially bind membranes containing cholesterol. Nap-22 is a crucial protein active in neurite outgrowth and synaptic plasticity.
PRODUCT SPECIFIC PUBLICATIONS
- Louis N. Manganas. et al. BASP1 labels neural stem cells in the neurogenic niches of mammalian brain. Sci Rep-Uk. 2021 Mar;11(1):1-18Read more>>
- Zhangdi Xu. et al. Construction of a TAN-associated risk score model with integrated multi-omics data analysis and clinical validation in gastric cancer. LIFE SCI. 2024 Jul;349:122731Read more>>
VALIDATION IMAGES
Antigen: bs-8662P, 0.2ug/100ul \nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \nSecondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000;\nTMB staining;\nRead the data in MicroplateReader by 450