bs-8675R [Primary Antibody]
BDKRB1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: BDKRB1

Immunogen Range: 161-260/353


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 623

Swiss Prot: P46663

Source: KLH conjugated synthetic peptide derived from human BDKRB1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
ICC(1:100-500)

Predicted Molecular Weight: 40


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Liu et al. Kinin B1 receptor as a novel, prognostic progression biomarker for carotid atherosclerotic plaques. (2017) Mol.Med.Rep. 16:8930-8936Read more>>
  • Gao et al. The Combination of Human Urinary Kallidinogenase and Mild Hypothermia Protects Adult Rats Against Hypoxic-Ischemic Encephalopathy-Induced Injury by Promoting Angiogenesis and Regeneration. (2018) Front.Aging.Neurosci. 10:196Read more>>
  • Shen Y et al. Elevated bradykinin receptor type 1 expression in postpartum acute myometritis: Possible involvement in augmented interstitial edema of the atonic gravid uterus. J Obstet Gynaecol Res. 2019 Jun 10.Read more>>
  • Qin L et al. Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis. Arthritis Res Ther. 2019 Jan 8;21(1):12. Read more>>
  • Debargha Basuli. et al. Kinin B1 Receptor Mediates Renal Injury and Remodeling in Hypertension. Front Med-Lausanne. 2021; 8: 780834Read more>>
  • Dong Zhang. et al. Aldh1a1 and Scl25a30 in diaphragmatic dysfunction:. EXP BIOL MED. Exp Biol Med. 0;()Read more>>
  • Wojciech Dyga. et al. The Role of Bradykinin Receptors in Hereditary Angioedema Due to C1-Inhibitor Deficiency. INT J MOL SCI. 2022 Jan;23(18):10332Read more>>
  • usco Indiara. et al. Kinin B1 and B2 receptors mediate cancer pain associated with both the tumor and oncology therapy using aromatase inhibitors. SCI REP-UK. 2023 Mar;13(1):1-16Read more>>
  • Jeimy Katherine Torres-Mndez. et al. Nicotinamide Prevents Diabetic Brain Inflammation via NAD+-Dependent Deacetylation Mechanisms. NUTRIENTS. 2023 Jan;15(14):3083Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human lung cancer labeled with Rabbit Anti-BDKRB1 Polyclonal Antibody, Unconjugated (bs-8675R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Lane 1: Mouse Liver tissue lysates; Lane 2: Human SiHa cell lysates; Lane 3: Human LOVO cell lysates; Lane 4: Human K562 cell lysates; Lane 5: Human U251 cell lysates probed with BDKRB1 Polyclonal Antibody, Unconjugated (bs-8675R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.