bs-9060R [Primary Antibody]
DVL2 (Thr224) Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: DVL2 Thr224

Specificity: This antibody will recognize DVL3 when phosphorylated at Thr205

Modification Site: Thr224

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1856

Swiss Prot: O14641

Source: KLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity).

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Predicted Molecular Weight: 79


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-phospho-DVL2(Thr224) Polyclonal Antibody, Unconjugated (bs-9060R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.