bs-9256R-Cy7

DATASHEET

Host: Rabbit

Target Protein: RNF113B

Immunogen Range: 151-250/322

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 140432

Source: KLH conjugated synthetic peptide derived from human RNF113B

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF113B (ring finger protein 113B), also referred to as zinc finger protein 183-like 1, RNF161, MGC26599, bA10G5.1 or ZNF183L1, is a 322 amino acid protein containing one C3H1-type zinc finger and one RING-type zinc finger. The gene encoding RNF113B maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Conjugation: Cy7

Excitation/ Emission: 743nm/767nm

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)

Predicted Cross Reactive Species: Human
Mouse
Rat
Cow
Sheep
Pig
Horse
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.