bs-9352R [Primary Antibody]
Proteasome 20S alpha 3 Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Proteasome 20S alpha 3

Immunogen Range: 155-255/255


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5684

Source: KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 3

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat
Others

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Peng\fei Zhang. et al. Integrated analysis of phosphoproteome and ubiquitylome in epididymal sperm of buffalo (Bubalus bubalis). Mol Reprod Dev. 2021 Jan;88(1):15-33Read more>>
VALIDATION IMAGES

Lane 1: Rat liver tissue lysates; Lane 2: Human Mcf-7 cell lysates; Lane 3: Human 293t cell lysates; Lane 4: Human Hepg2 cell lysates probed with PSMA3 (Proteasome 20S alpha 3) Polyclonal Antibody, Unconjugated (bs-9352R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.