bs-9391R [Primary Antibody]
SMURF1 Polyclonal Antibody
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DATASHEET

Host: Rabbit

Target Protein: SMURF1

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 57154

Source: KLH conjugated synthetic peptide derived from human SMURF1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Acts by mediating ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members.

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:500-2000)

Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Weng S et al. Improvement of muscular atrophy by AAVCSaCas9-mediated myostatin gene editing in aged mice. Cancer Gene Ther. 2020 Dec;27(12):960-975.Read more>>
  • Song Runjie. et al. A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer. MOL CANCER. 2023 Dec;22(1):1-2Read more>>
  • Xunhu Gu. et al. METTL14-Mediated m6A Modification of TUG1 Represses Ferroptosis in Alzheimer's Disease via Inhibiting GDF15 Ubiquitination. FRONT BIOSCI-LANDMRK. 2024 Aug;29(8):298Read more>>
VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with SMURF1 polyclonal antibody, unconjugated (bs-9391R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.