bs-9505R [Primary Antibody]
alpha 2 Macroglobulin Antibody
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Host: Rabbit

Target Protein: alpha 2 Macroglobulin

Immunogen Range: 751-850/1474


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2

Source: KLH conjugated synthetic peptide derived from human alpha 2 Macroglobulin

Purification: purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008].

Size: 100ul, 20uL

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IHC-P(1:200-400)

Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Cow
Horse
Chicken
Pig
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Hu, Hai Xia, et al. "Anti-inflammatory effects of Gualou Guizhi decoction in transient focal cerebral ischemic brains. Corrigendum in/mmr/12/3/3998." Molecular medicine reports 12.1 (2015): 1321-1327.Read more>>
  • Liu, Ranran, et al. "Uncovering the embryonic development-related proteome and metabolome signatures in breast muscle and intramuscular fat of fast-and slow-growing chickens." BMC Genomics 18.1 (2017): 816.Read more>>
  • Shu et al. Differentially expressed serum proteins associated with calcium regulation and hypocalcemia in dairy cows. (2017) Asian-Australas.J.Anim.Sc. 30:893-901Read more>>
VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with alpha 2 Macroglobulin polyclonal antibody, unconjugated (bs-9505R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.