bs-9553R [Primary Antibody]
RTL8C Polyclonal Antibody
www.biossusa.com
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DATASHEET

Host: Rabbit

Target Protein: RTL8C

Immunogen Range: 11-113/113


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8933

Source: KLH conjugated synthetic peptide derived from human CXX1/Cerebral protein 5

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The CXX1 gene product has been provisionally designated CXX1 pending further characterization.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Henke, Christine, et al. "Selective expression of sense and antisense transcripts of the sushi-ichi-related retrotransposon–derived family during mouse placentogenesis." Retrovirology 12.1 (2015): 1-17.Read more>>
VALIDATION IMAGES

This image was generously provided by Drs. Reiner Strick and Christine Henke at the University-Clinic Erlangen. Human placenta labeled with Rabbit Anti-Cerebral protein 5 Polyclonal Antibody, Unconjugated (bs-9553R) at 1:250. Positive and specific expression was found in the placenta bed with extravillous trophoblasts (left part) and partly with villi including syncytiothrophoblasts and endothelial cells (right part).