bs-9782R-A680

DATASHEET

Host: Rabbit

Target Protein: C1orf2

Immunogen Range: 151-250/668

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10712

Source: KLH conjugated synthetic peptide derived from human C1orf2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

COTE1, also known as FAM189B (family with sequence similarity 189, member B), is a 668 amino acid multi-pass membrane protein that is widely expressed and belongs to the FAM189 family. Existing as two alternatively spliced isoforms, COTE1 is encoded by a gene that maps to human chromosome 1q22. As the largest human chromosome, chromosome 1 spans about 260 million base pairs and makes up approximately 8% of the human genome. Hutchinson-Gilford progeria, a rare aging disorder, is associated with the LMNA gene which is located on chromosome 1. Familial adenomatous polyposis, Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Conjugation: ALEXA FLUOR® 680

Excitation/ Emission: 679nm/702nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.