bs-9806R

DATASHEET

Host: Rabbit

Target Protein: C2orf28

Immunogen Range: 51-150/229

Clonality: Polyclonal

Isotype: IgG

Source: KLH conjugated synthetic peptide derived from human C2orf28

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

APR3, also known as C2orf28 or p18, is a 229 amino acid single-pass membrane protein that contains one EGF-like domain and exists as two alternatively spliced isoforms. Expressed at a low level in hematopoietic cell lines, APR3 is thought to be involved in apoptosis and may also play a role in hematopoietic development and differentiation. The gene encoding APR3 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.