bs-9897R [Primary Antibody]
Glycoprotein VI Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Glycoprotein VI

Immunogen Range: 121-220/339


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 51206

Swiss Prot: Q9HCN6

Source: KLH conjugated synthetic peptide derived from human GPVI/Glycoprotein VI

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity which may contribute to arterial and venous thrombus formation. GPVI is expressed in megakaryocytes and platelets. Patients deficient in GPVI suffer from mild hemorrhagic diathesis and their platelets fail to aggregate in response to collagen. There are three isoforms.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: Mouse Spleen Lysates; Lane 2: Mouse Testis Lysates; Lane 3: Rat Spleen Lysates; Lane 4: Rat Testis Lysates; Lane 5: Human K562 cell Lysates; Lane 6: Human U-2 OS cell Lysates. Probed with Glycoprotein VI polyclonal Antibody, unconjugated (bs-9897R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.