bsm-0991M

DATASHEET

Host: Mouse

Target Protein: HPV18 E6 protein

Immunogen Range: 75-158/158

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 1489088

Swiss Prot: P06463

Source: KLH conjugated synthetic peptide derived from HPV18 E6 protein

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Transcriptional transactivator. Binds double-stranded DNA (By similarity). Has transforming activity. Inactivates, with E6-AP ubiquitin-protein ligase, the human p53/TP53 tumor suppressor protein by targeting it to degradation. Binds and targets human MUPP1/MPDZ protein to degradation. Those two functions presumably contribute to transforming activity. Interaction with human FBLN1 protein also seems to be linked to cell transformation.

Size: 100ul

Concentration: 1ug/ul

Applications: IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Predicted Molecular Weight: 19

Cross Reactive Species: Virus
(HPV18)

For research use only. Not intended for diagnostic or therapeutic use.