bsm-1626M [Primary Antibody]
PSA (PA5) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: PSA

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 354

Swiss Prot: P07288

Source: Full length native protein purified from human

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Predicted Molecular Weight: 29


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhu, Jian-guo, et al. "Expression of SOCSs in human prostate cancer and their association in prognosis." Molecular and cellular biochemistry (2013): 1-9.Read more>>
  • Zhou, Jie, et al. "Spectrum-based and color-selective electrochemiluminescence immunoassay for determining human prostate specific antigen in near-infrared region." Talanta 165 (2017): 117-121.Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human prostate carcinoma labeled with Mouse Anti-PSA (PA5) Monoclonal Antibody, Unconjugated (bsm-1626M) at 1:200 followed by conjugation to the secondary antibody and DAB staining\n