bsm-30151H-PE-CY5

DATASHEET

Host: Hamster

Target Protein: T-cell surface glycoprotein CD3 epsilon chain

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 12501

Swiss Prot: P22646

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 243l staining volume)

Predicted Molecular Weight: 20

Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.