bsm-30152A-PE-CY7 [Flow Cytometry]
mouse CD4/PE-Cy7
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Host: Rat

Target Protein: T-cell surface glycoprotein CD4

Clonality: Monoclonal

Isotype: IgG2b/Kappa

Entrez Gene: 12504

Swiss Prot: P06332

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 253l staining volume)

Predicted Molecular Weight: 48


Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.