bsm-30169H-PE

DATASHEET

Host: Hamster

Target Protein: Cytotoxic T-lymphocyte protein 4

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 12477

Swiss Prot: P09793

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8°C

Background:

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10ul/10^6 cells in 100ul)

Predicted Molecular Weight: 21

Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.