DATASHEET
Host:
Mouse
Target Protein:
CD48 antigen
Clonality:
Monoclonal
Isotype:
IgG1/Kappa
Entrez Gene:
962
Swiss Prot:
P09326
Purification:
Affinity purified by Protein G
Storage Buffer:
0.01M PBS, 0.5%BSA, 0.02% Proclin300
Storage:
Store at 2-8°C
Background:
This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]