DATASHEET
Host:
Rat
Target Protein:
Prominin-1
Clonality:
Monoclonal
Entrez Gene:
19126
Swiss Prot:
O54990
Purification:
Affinity purified by Protein G
Storage Buffer:
0.01M PBS, 0.5%BSA, 0.02% Proclin300
Storage:
Store at 2-8°C
Background:
Predicted to enable actinin binding activity; cadherin binding activity; and cholesterol binding activity. Involved in camera-type eye photoreceptor cell differentiation and retina layer formation. Located in several cellular components, including brush border; photoreceptor outer segment; and prominosome. Is integral component of plasma membrane. Is expressed in several structures, including epithelium; eye; future hindbrain; genitourinary system; and nervous system. Used to study retinitis pigmentosa 41. Human ortholog(s) of this gene implicated in cone-rod dystrophy 12 and retinitis pigmentosa 41. Orthologous to human PROM1 (prominin 1). [provided by Alliance of Genome Resources, Apr 2022]