bsm-30303M-FITC

DATASHEET

Host: Mouse

Target Protein: CD27 antigen

Clonality: Monoclonal

Isotype: IgG1/Kappa

Entrez Gene: 939

Swiss Prot: P26842

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8°C

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10ul/10^6 cells in 100ul)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.