DATASHEET
Host:
Mouse
Target Protein:
COX4I1
Clonality:
Monoclonal
Isotype:
IgG
Entrez Gene:
1327
Source:
Recombinant human COX4 protein
Purification:
Purified by Protein G.
Storage Buffer:
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
PRODUCT SPECIFIC PUBLICATIONS
- Li LL et al. ATPR Induces Acute Promyelocytic Leukemia Cells Differentiation and Growth Arrest by Blockade of SHP2/Rho/ROCK1 Pathway. Toxicol Appl Pharmacol
. 2020 May 15;399:115053. Read more>>
- Chen, Ying. et al. Elevated SFXN2 limits mitochondrial autophagy and increases iron-mediated energy production to promote multiple myeloma cell proliferation. CELL DEATH DIS. 2022 Sep;13(9):1-14Read more>>
- Han Yan. et al. FAM3A maintains metabolic homeostasis by interacting with F1-ATP synthase to regulate the activity and assembly of ATP synthase. METABOLISM. 2022 Dec;:155372Read more>>
- Yixian Ren. et al. CDK5-USP30 signaling pathway regulates MAVS-mediated inflammation via suppressing mitophagy in MPTP/MPP+ PD model. ECOTOX ENVIRON SAFE. 2024 Jul;279:116446Read more>>
VALIDATION IMAGES
Paraformaldehyde-fixed, paraffin embedded Mouse Heart; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Incubation: COX4I1 Monoclonal Antibody, conjugated (bsm-33037M-Cy3) at 1:200 overnight at 4°C; DAPI (blue, C02-04002) was used to stain the cell nuclei.
Paraformaldehyde-fixed, paraffin embedded Human Small Intestine; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Incubation: COX4I1 Monoclonal Antibody, conjugated (bsm-33037M-Cy3) at 1:200 overnight at 4°C; DAPI (blue, C02-04002) was used to stain the cell nuclei.