bsm-33052M-PerCP-Cy7 [Conjugated Primary Antibody]
CD45 Monoclonal Antibody, PerCP-Cy7 Conjugated
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Host: Mouse

Target Protein: CD45

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 5788

Swiss Prot: P08575

Source: Recombinant human CD45

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.

Conjugation: PerCP-Cy7

Excitation/ Emission: 482nm/780nm

Size: 100uL

Concentration: 1ug/ul

Applications: WB(1:500-2000)
ELISA(1:100-500)
FCM(1:100-500)
IHC-P(1:100-500)
IHC-F(1:100-500)

Predicted Molecular Weight: 143


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Smriti Arora. et al. Antibody mediated cotton-archetypal substrate for enumeration of circulating tumor cells and chemotherapy outcome in 3D tumors. Lab Chip. 2022 FebRead more>>
VALIDATION IMAGES