bsm-33061M-Cy5

DATASHEET

Host: Mouse

Target Protein: Cytokeratin 8

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 3856

Swiss Prot: P05787

Source: Recombinant human CK8

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul, 20uL

Concentration: Lot Dependent

Applications: IHC-F(1:100-500)
IF(IHC-P)(1:100-500)
IF(ICC)(1:50-200)
IF(1:50-200)
IHC-P(1:100-500)

Predicted Molecular Weight: 53 kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.