Host: Mouse
Target Protein: IL2RA/CD25
Clonality: Monoclonal
Isotype: IgG
Entrez Gene: 3559
Swiss Prot: P01589
Source: KLH conjugated synthetic peptide derived from human IL2RA/CD25
Purification: Purified by Protein G.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
Conjugation: Cy3
Excitation/ Emission: 512,550nm/570,615nm
Size: 100ul
Concentration: 1mg/ml
Applications: FCM(1:100)
Predicted Molecular Weight: 28
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.