bsm-33308M-BF750

DATASHEET

Host: Mouse

Target Protein: Actin, alpha skeletal muscle

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 58

Swiss Prot: P68133

Source: KLH conjugated synthetic peptide derived from human ACTA1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]

Conjugation: AbBy Fluor-750

Excitation/ Emission: 749nm/775nm

Size: 100µL

Concentration: 1ug/ul

Applications: WB(WB=1:2000-5000)
IHC-P(IHC-P=1:500-1000)
IHC-F(IHC-F=1:500-1000)
IF(IF=1:500-1000)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.