bsm-34186M-RBITC

DATASHEET

Host: Mouse

Target Protein: MUM1

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 84939

Swiss Prot: Q2TAK8

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity). Also involved in secretory granule priming in insulin secretion (By similarity). Interacts with FBXO45 (via SRY domain); leading to the degradation of UNC13A by the proteasome (By similarity).

Conjugation: RBITC

Excitation/ Emission: 570nm/595nm

Size: 100µL

Concentration: 1ug/ul

Applications: IF(IHC-P)(IF(IHC-P)(1:100-500))

Predicted Molecular Weight: 79

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.