bsm-4713M-Biotin

DATASHEET

Host: Mouse

Target Protein: beta-Amyloid 1-42

Clonality: Monoclonal

Isotype: IgG

Entrez Gene: 351

Source: KLH conjugated synthetic peptide derived from human beta-Amyloid (1-42)

Purification: Purified by Protein G.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µL

Concentration: 1ug/ul

Applications: WB(WB(1:500-2000))
IHC-P(IHC-P(1:500-5000))
IHC-F(IHC-F(1:500-5000))

Cross Reactive Species: Human
Rat
Bovine
Dog
Pig
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.