bsm-50226M [Primary Antibody]
Complement factor B (28A3) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: Complement factor B

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 629

Swiss Prot: P00751

Source: Protein purified from Human plasma

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store for 1 year at -20°C from date of shipment. Store for 1 year at -20°C from date of shipment.

Background:

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Size: 100ul

Concentration: 4ug/ul

Predicted Molecular Weight: 86


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1 : Human Serum (0.5uL); Lane 2 : Human Serum (1.0uL) probed with bsm-50226M Complement factor B (28A3) Monoclonal Antibody at 4.0ug/mL (1:250) and incubated at 4℃ overnight, followed by secondary antibody incubation for 60min at room temperature.