Target Protein: Complement factor B
Entrez Gene: 629
Swiss Prot: P00751
Source: Protein purified from Human plasma
Purification: Purified by Protein G.
Storage Buffer: HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
Storage: Store for 1 year at -20°C from date of shipment. Store for 1 year at -20°C from date of shipment.
Background: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Predicted Molecular Weight: 86
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.