bsm-51027M

DATASHEET

Host: Mouse

Target Protein: ITA6

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 3655

Swiss Prot: P23229

Source: ITA6 recombinant protein is used to produce this monoclonal antibody.

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purifie

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IF(1:50-200)
FCM(1:200-400)
IHC-P(1:200-400)

Predicted Molecular Weight: 127

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.