bsm-51112M

DATASHEET

Host: Mouse

Target Protein: TLE1

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 7088

Swiss Prot: Q04724

Source: This TLE1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the Central region of human TLE1.

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 83

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.