bsm-51142M

DATASHEET

Host: Mouse

Target Protein: SOX2

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 6657

Swiss Prot: P48431

Source: SOX2 recombinant protein

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purifie

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.

Size: 100uL

Concentration: 0.5ug/ul

Applications: WB(1:300-5000)
FCM(1:500-1000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 34

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.