bsm-51215M-HRP [Conjugated Primary Antibody]
Hsp90 (3C9) Monoclonal Antibody, HRP Conjugated
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Host: Mouse

Target Protein: Hsp90

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 3320

Swiss Prot: P07900

Source: This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 150-400 amino acids from human.

Purification: Purified by Protein G.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Conjugation: HRP

Excitation/ Emission: N/A

Size: 100µL

Concentration: 0.5ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 85


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Gaoqian Zhao. et al. Biomimetic Platform Based on Mesoporous Platinum for Multisynergistic Cancer Therapy. Acs Biomater Sci Eng. 2021;XXXX(XXX):XXX-XXXRead more>>
  • Ali Tugrul Akin. et al. Chloroquine attenuates chronic hypoxia-induced testicular damage via suppressing endoplasmic reticulum stress and apoptosis in experimental rat model. CLIN EXP PHARMACOL P. 2022 May 17Read more>>
  • Kerschbamer Emanuela. et al. CHD8 suppression impacts on histone H3 lysine 36 trimethylation and alters RNA alternative splicing. NUCLEIC ACIDS RES. 2022 Dec;50(22):12809-12828Read more>>
  • Osman Ahmet Polat. et al. Evaluation of histologic, antiapoptotic and antioxidant effects of melatonin against the acute ocular toxicity of Cisplatin. TISSUE CELL. 2023 Dec;85:102226Read more>>
  • G.F. Sengl. et al. Hsc70 phosphorylation patterns and calmodulin regulate AP2 Clathrin-Coated-Vesicle life span for cell adhesion protein transport. BBA-MOL CELL RES. 2024 Jan;1871:119611Read more>>
VALIDATION IMAGES