bsm-51223M [Primary Antibody]
UCH37 (8G6) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: UCH37

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 51377

Swiss Prot: Q9Y5K5

Source: Purified His-tagged UCH37 protein was used to produced this monoclonal antibody.

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 38


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: 293 Cell lysates; Lane 2: HeLa Cell lysates; Lane 3: 293T Cell lysates; probed with UCH37 (8G6) Monoclonal Antibody, unconjugated (bsm-51223M) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.