bsm-51231M [Primary Antibody]
CCRK (5C1) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: CCRK

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 23552

Swiss Prot: Q8IZL9

Source: Purified His-tagged CCRK protein was used to produced this monoclonal antibody.

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 39


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: MCF-7 Cell lysates; Lane 2: A549 Cell lysates; probed with CCRK (885CT27.1.1) Monoclonal Antibody, unconjugated (bsm-51231M) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.