bsm-51261M [Primary Antibody]
CDK5 (1C9) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: CDK5

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 1020

Swiss Prot: Q00535

Source: This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 160-286 amino acids from human.

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 33


Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: HeLa Cell lysates; Lane 2: mouse brain lysates; probed with CDK5 (1C9) Monoclonal Antibody, unconjugated (bsm-51261M) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.