bsm-51318M [Primary Antibody]
DENR (2C9) Monoclonal Antibody
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Host: Mouse

Target Protein: DENR

Clonality: Monoclonal

Isotype: IgG2b

Entrez Gene: 8562

Swiss Prot: O43583

Source: This DENR antibody is generated from a mouse immunized with a recombinant protein of human DENR.

Purification: Purified by Protein G.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IF(ICC)(1:50-200)
IF(1:50-200)
FCM(1:20-100)
IHC-P(1:200-400)

Predicted Molecular Weight: 22


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.