bsm-51407M [Primary Antibody]
CBX8 (12C7) Monoclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: CBX8

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 57332

Swiss Prot: Q9HC52

Source: This CBX8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the C-terminal region of human CBX8.

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 43


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: A549 lysates; Lane 2:HeLa lysates; probed with CBX8 (12C7) Monoclonal Antibody, unconjugated (bsm-51407M) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.