bsm-51593M [Primary Antibody]
CBX8 Monoclonal Antibody
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Host: Mouse

Target Protein: CBX8

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 57332

Swiss Prot: Q9HC52

Source: KLH conjugated synthetic peptide derived from human CBX8

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

Component of a Polycomb group (PcG) multiproteinPRC1-like complex, a complex class required to maintain thetranscriptionally repressive state of many genes, including Hoxgenes, throughout development. PcG PRC1 complex acts via chromatinremodeling and modification of histones; it mediatesmonoubiquitination of histone H2A 'Lys-119', rendering chromatinheritably changed in its expressibility.

Size: 100µL

Concentration: 0.5ug/ul

Applications: WB(WB=1:500-1000)
Flow-Cyt(Flow-Cyt=1:25)

Predicted Molecular Weight: 43


Predicted Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Lane 1: 293 cell lysates; Lane 2: Hela cell lysates; Lane 3: A549 cell lysates probed with CBX8 Monoclonal Antibody, Unconjugated (bsm-51593M) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.